Metformin Hydrochloride Tablets 500mg MT Oral Antihyperglycemic Medication 100pcs

Metformin Hydrochloride Tablets 500mg MT Oral Antihyperglycemic Medication 100pcs

Metformin Hydrochloride Tablets 500mg MT, also known as メトホルミン塩酸塩錠500mgMT, is an oral antihyperglycemic medication belonging to the biguanide class. It is commonly used in the management of type 2 diabetes mellitus as part of a comprehensive treatment plan that includes diet therapy and exercise therapy.

Each tablet contains 500mg of metformin hydrochloride. Metformin helps control blood glucose levels by reducing hepatic glucose production, improving insulin sensitivity, and enhancing peripheral glucose uptake. It is generally used under the direction of a doctor, pharmacist, or qualified healthcare professional.

Product Information

• Product Name: Metformin Hydrochloride Tablets 500mg MT
• Japanese Name: メトホルミン塩酸塩錠500mgMT
• Chinese Name: 日醫工鹽酸二甲雙胍錠
• Active Ingredient: Metformin Hydrochloride
• Strength: 500mg per tablet
• Package Size: 500mg x 100pcs
• Product Type: Oral antihyperglycemic medication
• Drug Class: Biguanide antidiabetic agent
• Dosage Form: Tablet
• Route of Administration: Oral
• Primary Indication: Type 2 diabetes mellitus
• Manufacturer Reference: Nichi-Iko Pharmaceutical / 日医工株式会社
• Japanese Product Reference: メトホルミン塩酸塩錠500mgMT「日医工」

Indications

Metformin Hydrochloride Tablets 500mg MT are commonly indicated for:

• Management of blood glucose levels in patients with type 2 diabetes mellitus
• Use as part of diabetes management with diet therapy and exercise therapy
• Use when diet and exercise therapy alone are not sufficient
• Use in combination with other antidiabetic medications when directed by a healthcare professional
• Ovulation induction in polycystic ovary syndrome when specifically prescribed
• Controlled ovarian stimulation in assisted reproductive technology for polycystic ovary syndrome when specifically prescribed

For polycystic ovary syndrome-related use, this medication should only be used under specialist medical supervision and according to the patient’s clinical condition.

How It Works

Metformin hydrochloride works mainly by decreasing glucose production in the liver. It also helps improve insulin sensitivity and supports glucose uptake in peripheral tissues such as muscle. These actions help reduce elevated blood glucose levels in people with type 2 diabetes.

Key Benefits

• Helps manage blood glucose levels in type 2 diabetes mellitus
• Supports diabetes treatment when combined with diet and exercise therapy
• May be used alone or with other antidiabetic medications as directed
• Biguanide class oral medication with established use in diabetes care
• Generally considered weight-neutral or associated with modest weight reduction in some patients
• May be prescribed for selected PCOS-related indications under medical supervision
• Convenient 500mg tablet strength

Usage and Dosage

Use only as directed by a doctor, pharmacist, or healthcare professional. Dosage may vary depending on age, medical condition, blood glucose levels, kidney function, tolerance, and other medications being used.

For Type 2 Diabetes

Adults generally start with 500mg of metformin hydrochloride per day, taken orally in divided doses two to three times daily, immediately before or after meals. The maintenance dose is determined according to treatment response and tolerance, and is commonly 750mg to 1,500mg per day. The dose may be adjusted by a healthcare professional, up to a maximum daily dose of 2,250mg.

For children aged 10 years or older, the usual starting dose is 500mg per day, divided into two to three doses taken just before or after meals. The maintenance dose is usually 500mg to 1,500mg per day, with a maximum daily dose of 2,000mg, as directed by a healthcare professional.

For Ovulation Induction in Polycystic Ovary Syndrome

When used in combination with other ovulation-inducing drugs, the usual starting dose is 500mg once daily. The dose may be increased gradually while checking tolerance, not exceeding 1,500mg per day, divided into two to three doses. The medication should be discontinued before ovulation, according to medical instructions.

For Controlled Ovarian Stimulation in Assisted Reproductive Technology for PCOS

When used in combination with other ovarian stimulants, the usual starting dose is 500mg once daily. The dose may be increased gradually while checking tolerance, not exceeding 1,500mg per day, divided into two to three doses. The medication should be discontinued before egg collection, according to medical instructions.

Administration Instructions

• Take orally with or immediately before or after meals.
• Taking metformin with meals may help reduce gastrointestinal side effects.
• Swallow tablets with water.
• Do not change the dose or frequency without medical advice.
• If you miss a dose, follow the instructions provided by your healthcare provider.
• Continue diet and exercise therapy as recommended by your healthcare professional.

Recommended For

• Adults with type 2 diabetes mellitus who require blood glucose management
• Patients whose blood glucose is not adequately controlled with diet and exercise alone
• Patients who need combination therapy with other antidiabetic medicines as prescribed
• Children aged 10 years or older with type 2 diabetes when prescribed by a doctor
• Selected patients with PCOS-related indications when prescribed by a specialist

Potential Side Effects

Possible side effects may include:

• Nausea
• Vomiting
• Diarrhea
• Abdominal discomfort
• Loss of appetite
• Metallic taste
• Fatigue or weakness
• Vitamin B12 reduction with long-term use
• Hypoglycemia, especially when used with insulin or sulfonylurea medicines

Serious Warning: Lactic Acidosis

Although rare, lactic acidosis is a serious potential side effect of metformin. Seek medical attention immediately if symptoms such as unusual tiredness, severe weakness, muscle pain, breathing difficulty, abdominal pain, persistent vomiting, dizziness, feeling cold, slow or irregular heartbeat, or altered consciousness occur.

The risk of lactic acidosis may be higher in patients with kidney problems, liver disease, excessive alcohol intake, dehydration, severe infection, heart failure, shock, or conditions associated with low oxygen levels.

Important Precautions

• Use only under medical supervision.
• Do not use for weight loss unless specifically prescribed for a medical indication.
• Kidney function should be assessed before and during treatment.
• Inform your doctor if you have kidney disease, liver disease, heart failure, dehydration, infection, or heavy alcohol use.
• Inform your doctor before surgery or radiological procedures involving iodinated contrast media.
• Do not drink excessive alcohol while taking metformin.
• Monitor blood glucose as instructed by your healthcare provider.
• Pregnant or breastfeeding patients should consult a healthcare professional before use.
• Keep out of reach of children.

Storage

Store in a cool, dry place away from direct sunlight, heat, and moisture. Keep the tablets in the original packaging until use and keep out of reach of children.

Disclaimer

This product information is provided for general reference only and should not replace medical advice, diagnosis, or treatment. Metformin Hydrochloride Tablets 500mg MT are oral medication and should be used only under the direction of a doctor, pharmacist, or qualified healthcare professional. Individual response and dosage requirements may vary.