Regenovue Deep Plus

Regenovue Deep Plus with Lidocaine

Regenovue Deep Plus is a cross-linked hyaluronic acid (HA) dermal filler with lidocaine from NeoGenesis Co., Ltd., South Korea. It is the medium-firmness gel in the Regenovue range, designed for injection into the lower dermis and upper subcutaneous tissue to correct moderate to deep wrinkles and folds, including nasolabial folds, and for lip contouring. It contains 24 mg/ml cross-linked HA and 0.3% lidocaine. “Plus” indicates the version with lidocaine. Each box contains one 1.1 ml pre-filled syringe. For use by licensed physicians only.

Key Features

• Medium Firmness: Intended for placement in the lower dermis and upper subcutaneous tissue.
• HA 24 mg/ml: Non-animal hyaluronic acid, cross-linked with BDDE.
• With 0.3% Lidocaine: Included to help reduce discomfort during injection.
• 27G Needles: Supplied with two 27G needles.
• Reversible: Hyaluronic acid can be dissolved with hyaluronidase by a qualified practitioner.

The Regenovue Range

The Regenovue range includes three gels of increasing firmness, each available with lidocaine (“Plus”) or without. All three contain 24 mg/ml HA. They differ in gel firmness, not concentration. The physician selects the product according to the treatment area and tissue depth.

• Regenovue Fine / Fine Plus: The softest gel, for superficial wrinkles in the upper dermis.
• Regenovue Deep / Deep Plus: A medium gel for moderate to deep wrinkles, nasolabial folds and lips, in the lower dermis and upper subcutaneous tissue.
• Regenovue Sub-Q / Sub-Q Plus: The firmest gel, for deep wrinkles and volume in the lower subcutaneous tissue.

Intended Use

• Moderate to deep facial wrinkles and folds
• Nasolabial folds
• Lip contouring and augmentation

Treatment area, injection depth, technique and volume must follow the official Instructions for Use and the treating physician’s assessment. Results and duration vary between individuals.

Product Specifications

• Brand: Regenovue
• Product: Regenovue Deep Plus (with Lidocaine)
• Manufacturer: NeoGenesis Co., Ltd.
• Origin: South Korea
• Composition: Cross-linked hyaluronic acid 24 mg/ml, lidocaine hydrochloride 0.3%, phosphate-buffered saline
• Cross-Linker: BDDE
• Injection Depth: Lower dermis to upper subcutaneous tissue, as specified in the IFU
• Contents: 1 × 1.1 ml pre-filled syringe, 2 × 27G needles
• Shelf Life: Refer to the carton for the expiry date
• Product Type: Hyaluronic acid dermal filler (medical device)

Administration

• For use only by licensed physicians trained in facial anatomy, filler injection techniques and the management of filler complications.
• Inject under aseptic conditions at the depth specified in the IFU.
• Not intended for superficial fine lines or deep volume restoration. Other gels in the range are designed for those uses.
• Injection depth, technique, volume and treatment interval must follow the IFU and the treating physician’s judgment.
• Do not self-administer.

Precautions

• Common reactions include redness, swelling, pain, tenderness, itching and bruising at the injection site. Swelling may be more noticeable after lip treatment.
• Lumps, nodules, asymmetry, infection and delayed inflammatory reactions may occur.
• Accidental injection into a blood vessel can cause vascular occlusion, skin necrosis and, rarely, visual impairment or blindness. The lips and nasolabial area contain significant arteries.
• Contains lidocaine. Not suitable for people with known allergy to lidocaine or other amide-type local anaesthetics.
• Do not inject into areas with skin inflammation, infection (including active cold sores), open wounds or damaged skin.
• Hyaluronic acid can be dissolved with hyaluronidase. Practitioners should keep hyaluronidase and an emergency protocol available.
• Seek medical attention immediately for severe or increasing pain, skin blanching or colour change, or any change in vision after treatment.
• Do not use if the packaging is open or damaged, the syringe is cracked or the product is past its expiry date.
• Single use only. One syringe, one patient. Do not re-sterilise. Keep out of reach of children.

Who Should Consult a Physician First

• People with known allergy to hyaluronic acid, lidocaine or amide-type local anaesthetics
• Pregnant or breastfeeding women
• People with infection, inflammation or skin disease at the treatment area, including a history of cold sores when treating the lips
• People with bleeding disorders or taking anticoagulant or antiplatelet medication
• People with autoimmune disease, a tendency to hypertrophic scars or keloids, or severe allergies
• People with permanent fillers or implants in the treatment area
• People under 18 years of age

After Treatment

Follow the aftercare instructions in the IFU and those given by the treating physician.

Storage

Store at 2–25°C. Protect from direct sunlight and freezing. Refer to the carton for the expiry date.

Package Contents

• 1 × 1.1 ml pre-filled syringe of Regenovue Deep Plus
• 2 × 27G needles
• Instructions for Use

Important Notice

For professional healthcare use only. This information is for general product reference. It does not replace medical advice, the official Instructions for Use or local regulations. This product is not intended to diagnose, treat, cure or prevent any disease. Results vary between individuals.