Regenovue Sub-Q Plus

Regenovue Sub-Q Plus

Regenovue Sub-Q Plus is a cross-linked hyaluronic acid (HA) dermal filler with lidocaine from NeoGenesis Co., Ltd., South Korea. It is the firmest gel in the Regenovue range, designed for injection into the lower subcutaneous tissue to correct deep to severe wrinkles and folds and to restore facial volume, such as in the mid-face and chin. It contains 24 mg/ml cross-linked HA and 0.3% lidocaine to improve comfort during injection. Each box contains one 1.1 ml pre-filled syringe. For use by licensed physicians only.

Key Features

• Firmest Gel in the Range: Intended for placement in the lower subcutaneous tissue.
• HA 24 mg/ml: Non-animal hyaluronic acid, cross-linked with BDDE.
• With 0.3% Lidocaine: Helps reduce discomfort during injection. A version without lidocaine (Sub-Q) is also available.
• Reversible: Hyaluronic acid can be dissolved with hyaluronidase by a qualified practitioner.

The Regenovue Range

The Regenovue range includes three gels of increasing firmness, each available with lidocaine (“Plus”) or without. All three contain 24 mg/ml HA. They differ in gel firmness, not concentration. The physician selects the product according to the treatment area and tissue depth.

• Regenovue Fine / Fine Plus: The softest gel, for superficial wrinkles in the upper dermis.
• Regenovue Deep / Deep Plus: A medium gel for moderate to deep wrinkles, nasolabial folds and lips.
• Regenovue Sub-Q / Sub-Q Plus: The firmest gel, for deep wrinkles and volume in the lower subcutaneous tissue.

Intended Use

• Deep to severe facial wrinkles and folds
• Volume restoration of the mid-face and cheek area
• Chin volume and contour

Treatment area, injection depth, technique and volume must follow the official Instructions for Use and the treating physician’s assessment. Results and duration vary between individuals.

Product Specifications

• Brand: Regenovue
• Product: Regenovue Sub-Q Plus (with lidocaine)
• Manufacturer: NeoGenesis Co., Ltd.
• Origin: South Korea
• Composition: Cross-linked hyaluronic acid 24 mg/ml, lidocaine 0.3%, phosphate-buffered saline
• Cross-Linker: BDDE
• Injection Depth: Lower subcutaneous tissue, as specified in the IFU
• Contents: 1 × 1.1 ml pre-filled syringe, 2 needles
• Shelf Life: Refer to the carton for the expiry date
• Product Type: Hyaluronic acid dermal filler (medical device)

Administration

• For use only by licensed physicians trained in facial anatomy, filler injection techniques and the management of filler complications.
• Inject under aseptic conditions at the depth specified in the IFU.
• Not intended for superficial lines or the lips. Other gels in the range are designed for those uses.
• Confirm the patient has no allergy to lidocaine or other amide-type local anaesthetics before use.
• Injection depth, technique, volume and treatment interval must follow the IFU and the treating physician’s judgment.
• Do not self-administer.

Precautions

• Common reactions include redness, swelling, pain, tenderness, itching and bruising at the injection site.
• Lumps, nodules, asymmetry, product migration, infection and delayed inflammatory reactions may occur.
• Accidental injection into a blood vessel can cause vascular occlusion, skin necrosis and, rarely, visual impairment or blindness.
• The total lidocaine dose should be considered when combined with other local anaesthetics.
• Do not inject into areas with skin inflammation, infection, open wounds or damaged skin.
• Hyaluronic acid can be dissolved with hyaluronidase. Practitioners should keep hyaluronidase and an emergency protocol available.
• Seek medical attention immediately for severe or increasing pain, skin blanching or colour change, or any change in vision after treatment.
• Do not use if the packaging is open or damaged, the syringe is cracked or the product is past its expiry date.
• Single use only. One syringe, one patient. Do not re-sterilise. Keep out of reach of children.

Who Should Consult a Physician First

• People with known allergy to hyaluronic acid, lidocaine or other amide-type local anaesthetics, or any component of the product
• Pregnant or breastfeeding women
• People with infection, inflammation or skin disease at the treatment area
• People with bleeding disorders or taking anticoagulant or antiplatelet medication
• People with autoimmune disease, a tendency to hypertrophic scars or keloids, or severe allergies
• People with heart rhythm disorders, severe liver disease or porphyria
• People with permanent fillers or implants in the treatment area
• People under 18 years of age

After Treatment

Follow the aftercare instructions in the IFU and those given by the treating physician.

Storage

Store at 2–25°C. Protect from direct sunlight and freezing. Refer to the carton for the expiry date.

Package Contents

• 1 × 1.1 ml pre-filled syringe of Regenovue Sub-Q Plus
• 2 × needles
• Instructions for Use

Important Notice

For professional healthcare use only. This information is for general product reference. It does not replace medical advice, the official Instructions for Use or local regulations. This product is not intended to diagnose, treat, cure or prevent any disease. Results vary between individuals.